Issue 19, 1991

A practical and efficient method for the construction of the biphenyl framework; nucleophilic aromatic substitution on 2-methoxybenzoates with aryl grignard reagents

Abstract

Treatment of 2-methoxybenzoic esters derived from 2, 6-dialkylphenols with aryl Grignard reagents afforded 1,1′-biphenyl-2-carboxylates in excellent yields.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1991, 1375-1376

A practical and efficient method for the construction of the biphenyl framework; nucleophilic aromatic substitution on 2-methoxybenzoates with aryl grignard reagents

T. Hattori, T. Suzuki and S. Miyano, J. Chem. Soc., Chem. Commun., 1991, 1375 DOI: 10.1039/C39910001375

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