Issue 19, 1991

Base pairing of cytosine analogues with adenine and guanine in oligonucleotide duplexes: evidence for exchange between Watson–Crick and wobble base pairs using 1H NMR spectroscopy

Abstract

1 H NMR spectra of oligodeoxynucleotide duplexes incorporating N4-methoxycytosine and a related analogue paired with adenine and guanine demonstrate that Watson–Crick and wobble base pairs are in slow exchange on the chemical shift timescale.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1991, 1357-1359

Base pairing of cytosine analogues with adenine and guanine in oligonucleotide duplexes: evidence for exchange between Watson–Crick and wobble base pairs using 1H NMR spectroscopy

A. N. R. Nedderman, M. J. Stone, P. K. T. Lin, D. M. Brown and D. H. Williams, J. Chem. Soc., Chem. Commun., 1991, 1357 DOI: 10.1039/C39910001357

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