The reaction of 5-iodo-1,3-dioxin-4-ones with trifluoromethyl iodide in the presence of copper powder in hexamethylphosphoric triamide affords the title compounds, which can be converted either to α-trifluoromethylated β-keto acid derivatives or to uracil or oxazine derivatives bearing a trifluoromethyl group.
T. Iwaoka, M. Sato and C. Kaneko, J. Chem. Soc., Chem. Commun., 1991, 1241 DOI: 10.1039/C39910001241
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