Issue 17, 1991

Design and synthesis of cobalt(III) nitrogen mustard complexes as hypoxia selective cytotoxins. The X-ray crystal structure of bis(3-chloropentane-2,4-dionato)(RS-N,N′-bis(2-chloroethyl)ethylenediamine)cobalt(III) perchlorate, [Co(Clacac)2(bce)]ClO4

Abstract

The design, synthesis and biological evaluation of [Co(Meacac)2(dce)]+, a cobalt(III) nitrogen mustard complex that is effective as a hypoxia selective cytotoxin for potential anti-cancer use, is reported.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1991, 1171-1173

Design and synthesis of cobalt(III) nitrogen mustard complexes as hypoxia selective cytotoxins. The X-ray crystal structure of bis(3-chloropentane-2,4-dionato)(RS-N,N′-bis(2-chloroethyl)ethylenediamine)cobalt(III) perchlorate, [Co(Clacac)2(bce)]ClO4

D. C. Ware, W. R. Wilson, W. A. Denny and C. E. F. Rickard, J. Chem. Soc., Chem. Commun., 1991, 1171 DOI: 10.1039/C39910001171

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements