Crystal structure and isomerism of a tumour targeting radiopharmaceutical: [ReO(dmsa)2]–(H2dmsa =meso-2,3-dimercaptosuccinic acid)
Abstract
A crystal structure determination shows that one isomer of the complex anion [ReO(dmsa)2]–(H2dmsa =meso-2,3-dimercaptosuccinic acid), a compound which in radiopharmaceutical form has been shown to localise in certain human tumours, has a square-pyramidal structure with all carboxylic acid groups uncoordinated and oriented endo relative to the oxo ligand.