Decarboxylation of 2-aminomalonic acid catalysed by serine hydroxymethyltransferase is, in fact, a stereospecific process
Abstract
Contrary to previous reports, 2-aminomalonic acid is decarboxylated stereospecifically by serine hydroxymethyltransferase; the newly introduced hydrogen occupies the 2-pro-S position of the glycine product.