Enyzmatic cyclization of 2,3-dihydrosqualene into euph-7-ene by a cell-free system from the protozoon Tetrahymena pyriformis
Abstract
The cyclase of the protozoon Tetrahymena pyriformis, which normally converts squalene into the pentacyclic tetrahymanol, cyclized 2,3-dihydrosqualene into euph-7-ene with an unexpected tetracyclic skeleton and back-bone rearrangement.