The regiospecific addition of 2-potassio-2-nitropropane to the 4-arylidene-oxazol-5-ones followed by oxygenation led to 2-arylbutenoic acid imides, the key intermediate for several pharmacodynamic compounds in high yields.
N. Lalitha, U. T. Bhalerao and D. S. Iyengar, J. Chem. Soc., Chem. Commun., 1991, 897 DOI: 10.1039/C39910000897
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