Issue 2, 1991

Synthesis of (R)-(–)- and (S)-(+)-muscone of 100% optical purity by conjugate addition of chiral methylcuprate to (E)-cyclopentadec-2-enone

Abstract

Synthesis of (R)-(–)- and (S)-(+)-muscone of essentially 100% enantiomeric excess (e.e.) by the conjugate addition of chiral methylcuprate to (E)-cyclopentadec-2-enone was accomplished by adding small amounts of tetrahydrofuran (THF) as an external ligand to a toluene solution of the chiral methylcuprate.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1991, 101-102

Synthesis of (R)-(–)- and (S)-(+)-muscone of 100% optical purity by conjugate addition of chiral methylcuprate to (E)-cyclopentadec-2-enone

K. Tanaka and H. Suzuki, J. Chem. Soc., Chem. Commun., 1991, 101 DOI: 10.1039/C39910000101

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements