A new type of protected mesoionic triazoline nucleoside was synthesized by the reaction of protected 1,2-dideoxy-hydrazino-D-ribose or 1-deoxy-hydrazino-D-ribose with isothiouronium compounds. The three compounds obtained 10a, 10f and 16a were deprotected with tetrabutylammonium fluoride. They showed no activity against HSV-1 virus.
M. Yokoyama, T. Ikuma, N. Obara and H. Togo, J. Chem. Soc., Perkin Trans. 1, 1990, 3243 DOI: 10.1039/P19900003243
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