Issue 11, 1990
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Acyl radical cyclizations in synthesis. Part 3. Synthesis of (±)-trans-3,5-bis-(t-butyldimethylsiloxy)-2-methylenecyclohexanone, an ‘A’ ring model for 1α, 25-dihydroxyvitamin D3

Duncan Batty,   David Crich  and  Simon M. Fortt  

Abstract

A concise synthesis of (±)-trans-3,5-bis(t-butyldimethylsiloxy)-2-methylenecyclohexanone has been developed. The synthesis proceeds in seven steps from ethyl acetoacetate and involves a highly efficient acyl radical cyclization to construct the six-membered ring.

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/P19900002875
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1990, 2875-2879

Permissions

Request permissions

Acyl radical cyclizations in synthesis. Part 3. Synthesis of (±)-trans-3,5-bis-(t-butyldimethylsiloxy)-2-methylenecyclohexanone, an ‘A’ ring model for 1α, 25-dihydroxyvitamin D3

D. Batty, D. Crich and S. M. Fortt, J. Chem. Soc., Perkin Trans. 1, 1990, 2875 DOI: 10.1039/P19900002875

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements