Issue 9, 1990

A convenient chemoenzymatic synthesis of (R)- and (S)-(chloromethyl)oxirane

Abstract

(R)- and (S)-1-Chloro-3-tosyloxypropan-2-ol have been prepared by biocatalysed enantioselective esterification in hexane, and in turn could be readily converted into optically active (chloromethyl)oxirane in high yield.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1990, 2559-2561

A convenient chemoenzymatic synthesis of (R)- and (S)-(chloromethyl)oxirane

C. Chen, Y. Liu and M. Marsella, J. Chem. Soc., Perkin Trans. 1, 1990, 2559 DOI: 10.1039/P19900002559

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