Enantioselective synthesis of (+)-endo- and (–)-exo-1,3-dimethyl-2,9-dioxabicyclo[3.3.1]nonane
Abstract
The title compounds, one of which is a host-specific substance isolated from the Norway Spruce Picea abies infested by the ambrosia beetle Trypodendron lineatum, have been synthesised in an enantioselective and diastereospecific manner using the Sharpless asymmetric epoxidation as the key step and source of optical activity.