New preparative and optical resolution method for β-lactams
Abstract
Photoirradiation of a 1 : 1 inclusion compound of oxoamide and N,N,N′,N′-tetracyclohexylbiphenyl-2,2′-dicarboxamide in the solid state gave a β-lactam, which was resolved by complexation with optically active 9,9′-biphenanthryl-10,10′-diol. Chiral recognition of the host and guest in the inclusion compound was studied by X-ray crystallographic analysis.