Issue 3, 1990

Homochiral fluoro-organic compounds. Synthesis of the two enantiomers of (Z)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-ol through microbial reduction

Abstract

The reduction of (Z)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-one with growing cultures of Geotrichum candidum and Phanerochaete chrysosporium afforded (S)- and (R)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-ol in enantiomerically pure form.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1990, 579-583

Homochiral fluoro-organic compounds. Synthesis of the two enantiomers of (Z)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-ol through microbial reduction

R. Bernardi, P. Bravo, R. Cardillo, D. Ghiringhelli and G. Resnati, J. Chem. Soc., Perkin Trans. 1, 1990, 579 DOI: 10.1039/P19900000579

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