Bis(o-t-butoxycarbonyltetrachlorobenzoyl) groups effectively protect the guanidino group of arginine during peptide synthesis; they are cleaved in a two-stage process by treatment with trifluoroacetic acid and then with very dilute acid.
T. Johnson and R. C. Sheppard, J. Chem. Soc., Chem. Commun., 1990, 1605 DOI: 10.1039/C39900001605
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