Synthesis of new carbocyclic analogues of 3′-azido- and 3′-amino-2′,3′-dideoxynucleosides

Abstract

A route is described for the synthesis of cyclopentane analogues of 1-(3′-azido- and 3′-amino-2′,3′-dideoxy-β-erythro-pentofuranosyl)-5-iodouracil and -(E)-5-(2-bromovinyl)uracil, compounds of interest as potential antiviral and/or antitumour agents.