Issue 21, 1990

Tricyclic analogues of artemisinin: synthesis and antimalarial activity of (+)-4,5-secoartemisinin and (–)-5-nor-4,5-secoartemisinin

Abstract

Two ring-A cleaved analogues of the natural product artemisinin have been synthesized and examined for in vitro antimalarial activity.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1990, 1487-1489

Tricyclic analogues of artemisinin: synthesis and antimalarial activity of (+)-4,5-secoartemisinin and (–)-5-nor-4,5-secoartemisinin

M. A. Avery, W. K. M. Chong and J. E. Bupp, J. Chem. Soc., Chem. Commun., 1990, 1487 DOI: 10.1039/C39900001487

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