Issue 18, 1990

A regioselective, stereoselective synthesis of a diacylglycerophosphocholine hydroperoxide by use of lipoxygenase and lipase

Abstract

1-Stearoyl-2-[13′-(S)-hydroperoxy-(9′Z, 11′E)-octadecadienoyl]-sn-glycero-3-phosphocholine (11) was synthesized without contamination by any regio- and stereo-chemical isomers by a combination of lipoxygenase-catalysed peroxidation, lipase-catalysed stearoylation, and dicyclohexyl carbodiimide-mediated (DCC) esterification.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1990, 1281-1282

A regioselective, stereoselective synthesis of a diacylglycerophosphocholine hydroperoxide by use of lipoxygenase and lipase

N. Baba, K. Yoneda, S. Tahara, J. Iwasa, T. Kaneko and M. Matsuo, J. Chem. Soc., Chem. Commun., 1990, 1281 DOI: 10.1039/C39900001281

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