A total synthesis of (+)-isovelleral. The absolute configuration of the russulaceae sesquiterpenes
Abstract
(+)-Isovelleral, an antibiotic and antifeedant sesquiterpene dialdehyde from Basidiomycetes, has been synthesised via a diastereoselective intramolecular Diels–Alder cyclisation of a chiral intermediate derived from D-ribonolactone.