Issue 3, 1990

Large extra-cavity contributions to hydrophobic binding of lipophilic substrates in synthetic receptor models

Abstract

On the basis of equilibrium constants with macrocyclic azonia cyclophanes, of complexation induced NMR shifts, and of computer simulated structures, it is shown that lipophilic guest parts extending out of the host cavity greatly enhance the binding in water.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1990, 276-278

Large extra-cavity contributions to hydrophobic binding of lipophilic substrates in synthetic receptor models

H. Schneider, R. Kramer, I. Theis and M. Zhou, J. Chem. Soc., Chem. Commun., 1990, 276 DOI: 10.1039/C39900000276

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