The macrobicyclic ligand cryptand 222 can interact with amino acids in methanol to form stable 1 : 1 complexes; thermodynamic data for these complexation reactions are first reported and together with computer calculations, these suggest active sites on both guest and receptor molecules.
A. F. D. de Namor, M. C. Ritt, M. Schwing-Weill, F. A. Neu and D. F. V. Lewis, J. Chem. Soc., Chem. Commun., 1990, 116 DOI: 10.1039/C39900000116
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