Issue 1, 1990

Ketene dithioacetals as 1,3-dipolarophiles. Applications to the synthesis of cyclic amino acids

Abstract

Intramolecular azide cycloaddition reactions of ketene dithioacetals provide a new route to cyclic amino acids and a stereoselective synthesis of (2S,3S,4R)-3,4-dihydroxyproline (14) based on this methodology is described.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1990, 51-53

Ketene dithioacetals as 1,3-dipolarophiles. Applications to the synthesis of cyclic amino acids

W. O. Moss, R. H. Bradbury, N. J. Hales and T. Gallagher, J. Chem. Soc., Chem. Commun., 1990, 51 DOI: 10.1039/C39900000051

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