Voltammetric behaviour of immunoglobulin G at stationary mercury electrodes

Abstract

A.c. voltammetric measurements have shown that bovine and human immunoglobulin G are adsorbed at a mercury electrode over a broad potential range and at open circuit. A current signal at ca.–0.55 V was identified as being due to an interfacial process connected with reversible protein re-orientations in the adsorption layer and, possibly, with fast faradaic reactions of both adsorbed redox states of the immunoglobulin.