When suspended in an organic solvent, α-chymotrypsin catalyzed peptide bond formation. Dipeptides containing D-amino acid components have been prepared. The importance of the water content of the system has been investigated.
J. M. Ricca and D. H. G. Crout, J. Chem. Soc., Perkin Trans. 1, 1989, 2126 DOI: 10.1039/P19890002126
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