π-Facial selectivity of the 1,3-dipolar cycloaddition of the parent azomethine ylide to homochiral dipolarophiles
Abstract
The 1,3-dipolar cycloaddition of the azomethine ylide (2) with homochiral cyclic dipolarophiles proceeds with high facial selectivity, whereas for homochiral acyclic dipolarophiles, the π-facial selectivity and mode of cycloaddition is dependent on the structure of the dipolarophile.