Issue 5, 1989

Addition of O-alkyl O′-trimethylsilyl ketene acetals to arynes generated from several aryl halides with NaNH2

Abstract

A number of alkyl-substituted aromatic carboxylic acids, in which an alkyl substituent and the carboxy group are situated ortho to each other, could be synthesized by treatment of O-alkyl O′-trimethylsilyl ketene acetals with several aryl halides in the presence of an excess of NaNH2 at room temperature followed by hydrolysis with aqueous hydrochloric acid.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1989, 915-918

Addition of O-alkyl O′-trimethylsilyl ketene acetals to arynes generated from several aryl halides with NaNH2

S. M. Ali and S. Tanimoto, J. Chem. Soc., Perkin Trans. 1, 1989, 915 DOI: 10.1039/P19890000915

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