Jump to main content
Jump to site search

Issue 8, 1989
Previous Article Next Article

A new chiral ferrocenylphosphine ligand with C2 symmetry: prepration and use for palladium-catalysed asymmetric cross-coupling

Abstract

A new chiral ferrocenylphosphine ligand, which has C2-symmetric structure and a functional group on the side chain, was prepared by ortho-lithiation and phosphination of 1,1′-bis[1-(N,N-dimethylamino)ethyl]ferrocene followed by optical resolution of the ditartrate salts and was found to be effective for palladium-catalysed asymmetric cross-coupling of 1-phenylethylzinc chloride with vinyl bromide giving 3-phenylbut-1-ene of over 90% e.e.

Back to tab navigation

Article type: Paper
DOI: 10.1039/C39890000495
Citation: J. Chem. Soc., Chem. Commun., 1989,0, 495-496
  •   Request permissions

    A new chiral ferrocenylphosphine ligand with C2 symmetry: prepration and use for palladium-catalysed asymmetric cross-coupling

    T. Hayashi, A. Yamamoto, M. Hojo and Y. Ito, J. Chem. Soc., Chem. Commun., 1989, 0, 495
    DOI: 10.1039/C39890000495

Search articles by author

Spotlight

Advertisements