Mono-hydrofluorination of electrophilic alkynes by the liquid biphasic CsF–H2O–DMF system (DMF = N,N-dimethylformamide)
Abstract
CsF induces the addition of HF in fair yields to activated acetylenic triple bonds in a DMF–water biphasic medium (DMF = N,N-dimethylformamide); in a homogeneous DMF–water mixture, no addition is observed.