SCHEDULED MAINTENANCE
Several 14-α-aminomethyl-substituted lanosterol derivatives have been synthesized involving a complete Δ7,8to Δ8,9isomerization; these compounds are inhibitors of fungal ergosterol biosynthesis and are active against intact Candida and dermatophyte strains.
A. B. Cooper, J. J. Wright, A. K. Ganguly, J. Desai, D. Loebenberg, R. Parmegiani, D. S. Feingold and I. J. Sud, J. Chem. Soc., Chem. Commun., 1989, 898 DOI: 10.1039/C39890000898
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