Tetra-aza-macrocycles covalently attached to a monoclonal antibody may be efficiently radiolabelled with 64Cu or 67Cu at pH 4, minimising non-specific binding to the protein, giving a kinetically stable conjugate in vivo.
J. R. Morphy, D. Parker, R. Kataky, A. Harrison, M. A. W. Eaton, A. Millican, A. Phipps and C. Walker, J. Chem. Soc., Chem. Commun., 1989, 792 DOI: 10.1039/C39890000792
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