Issue 12, 1989

Penicillin biosynthesis: stereochemical dependence on mode of second ring closure

Abstract

The stereochemical requirements for the conversion of tripeptides with unsaturated amino acids in the C-terminal position to bicyclic β-lactam products using isopenicillin N synthase was investigated using the diastereoisomeric peptides (7) and (12).

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1989, 758-761

Penicillin biosynthesis: stereochemical dependence on mode of second ring closure

J. E. Baldwin, R. M. Adlington, C. J. Schofield and H. Ting, J. Chem. Soc., Chem. Commun., 1989, 758 DOI: 10.1039/C39890000758

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