Issue 9, 1989

The chemical conversion of C-terminal glycines in peptides into taurine

Abstract

The first chemical conversion of C-glycine in dipeptides into taurine has been achieved using a general substitution of a sulpho group for a halogeno or mesyl group via the corresponding amino acid 2-halogenoethyl-or 2-methanesulphonyloxyethyl-amides, each of which was prepared from the ethanolamide obtained by LiBH4 reduction of a protected dipeptide containing a C-glycine ester.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1989, 521-522

The chemical conversion of C-terminal glycines in peptides into taurine

K. Higashiura, Y. Toyomaki and K. Ienaga, J. Chem. Soc., Chem. Commun., 1989, 521 DOI: 10.1039/C39890000521

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