Issue 3, 1989

Isolation and structure determination of a novel phorbol derivative in an intramolecular diester macrolide

Abstract

Three proteinkinase C-agonizing macrolides, formed by esterification of the novel phorbol derivative 11,18-dehydro-4,12-dideoxy-16-hydroxyphorbol with dicarboxylic acids, that differ only in the state of oxidation of a phenyl residue, were isolated from the dried leaves of Pycnocoma cornuta Muell. (Euphorbiaceae), and their structures were determined by n.m.r. studies.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1989, 183-184

Isolation and structure determination of a novel phorbol derivative in an intramolecular diester macrolide

K. Bergquist, H. Obianwu and B. Wickberg, J. Chem. Soc., Chem. Commun., 1989, 183 DOI: 10.1039/C39890000183

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