Cycloaddition of 2,3,4,5-tetrahydropyridine N-oxide to isobutyl vinyl ether and allyl alcohol; methyl 2- formylmethylpiperidine-1-carboxylate
Abstract
2,3,4,5-Tetrahydropyridine N-oxide undergoes cycloaddition with isobutyl vinyl ether and allyl alcohol to give the hexahydroisoxazolo[2,3-a] pyridines (3) and (4). In model experiments these were converted into methyl 2-formylmethylpiperidine-1-carboxylate (9).