Some transformations of 1,3-glycols utilizing dimethylformamide dimethyl acetal have been examined with the diterpenoids aphidicolin and foliol and some steroids as substrates. Axial alcohols with a suitably disposed trans hydrogen atom undergo an elimination reaction to give the formate of an unsaturated alcohol via the quaternary salt of the cyclic formamido acetal.
M. J. Ackland, J. F. Gordon, J. R. Hanson, B. L. Yeoh and A. H. Ratcliffe, J. Chem. Soc., Perkin Trans. 1, 1988, 2013 DOI: 10.1039/P19880002013
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