Issue 7, 1988

Nucleophilic reactions of α-aminoalkenenitriles

Abstract

Organo-lithium, -magnesium, and -zinc reagents add to α-aminoalkenenitriles in the 1,2-fashion to give α,β-unsaturated ketones, whereas organocuprate, sodium borohydride, sulphide ion, and sulphonestabilised carbanions react in the 1,4-fashion to furnish α-amino nitriles.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1988, 1945-1948

Nucleophilic reactions of α-aminoalkenenitriles

J. Fang and H. Chang, J. Chem. Soc., Perkin Trans. 1, 1988, 1945 DOI: 10.1039/P19880001945

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