Synthesis of 6-hydroxy-1,4-dimethylisoquinoline and of ethyl 7-hydroxy-6-methoxy-1-methylisoquinoline-3-carboxylate
Abstract
The syntheses of 6-methoxy- and 6-hydroxy-1,4-dimethylisoquinoline and of ethyl 7-hydroxy-6-methoxy-1-methylisoquinoline-3-carboxylate, key intermediates required for a synthetic approach1 to the antitumour antibiotic CC-1065, are described.