Stereochemistry of hydroboronation and osmylation of 3α,5-cycloandrost-6-en-17-one
Abstract
The stereochemistry of osmylation of a steroidal 6-ene is shown to be modified by the presence of a 3α,5-cyclopropane ring leading to predominantly β-face attack. Hydroboronation affords the 6α-,7α-, and 7β-alcohols.