ortho-Hydroxylation of aromatic aldehydes: a short synthesis of 2-hydroxypyrene-1-carbaldehyde
Abstract
A new methodology for the ortho-hydroxylation of aromatic aldehydes via ortho-lithiated aromatic amino alkoxides provides easy access to 2-hydroxypyrene-1-carbaldehyde, a valuable precursor for biologically important pyrenofurans and pyrenocoumarins.