A convergent and practical synthesis of (+)-isocarbacyclin has been accomplished, incorporating novel methods for linking α and ω appendages with a chiral bicyclo[3.3.0]octane nucleus.
S. Hashimoto, T. Shinoda and S. Ikegami, J. Chem. Soc., Chem. Commun., 1988, 1137 DOI: 10.1039/C39880001137
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