Issue 6, 1988

Modification of neutral (isoelectric) liposomes to anionic liposomes by phospholipase A2: the use of macrocyclic 1,2-dotriacontanedioyl-sn-glycero-3-phosphocholine

Abstract

1,2-Dotriacontanedioyl-sn-glycero-3-phosphocholine (dTPC) has been synthesized; liposomes containing dTPC were converted rapidly into anionic liposomes at pH 7 by the action of phospholipase A2, retaining the vesicular structure and exposing the CO2H groups of the lysolipids on the membrane surface.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1988, 445-446

Modification of neutral (isoelectric) liposomes to anionic liposomes by phospholipase A2: the use of macrocyclic 1,2-dotriacontanedioyl-sn-glycero-3-phosphocholine

K. Yamauchi, I. Yamamoto and M. Kinoshita, J. Chem. Soc., Chem. Commun., 1988, 445 DOI: 10.1039/C39880000445

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