Issue 5, 1988

Asymmetric induction by chiral silicon. Synthesis and electrophilic reactivity towards dienes and carbanions of R-(–)-methyl-α-naphthyl-phenylsilyl phenyl thioketone

Abstract

The title compound was prepared by acid catalysed reaction of the corresponding ketone with hydrogen sulphide, and its ability to transfer chirality to the carbon α to silicon in reactions with buta-1,3-diene and methyl-lithium was tested; good levels of asymmetric induction were observed.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1988, 365-367

Asymmetric induction by chiral silicon. Synthesis and electrophilic reactivity towards dienes and carbanions of R-(–)-methyl-α-naphthyl-phenylsilyl phenyl thioketone

B. F. Bonini, G. Mazzanti, P. Zani and G. Maccagnani, J. Chem. Soc., Chem. Commun., 1988, 365 DOI: 10.1039/C39880000365

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