Asymmetric induction by chiral silicon. Synthesis and electrophilic reactivity towards dienes and carbanions of R-(–)-methyl-α-naphthyl-phenylsilyl phenyl thioketone
Abstract
The title compound was prepared by acid catalysed reaction of the corresponding ketone with hydrogen sulphide, and its ability to transfer chirality to the carbon α to silicon in reactions with buta-1,3-diene and methyl-lithium was tested; good levels of asymmetric induction were observed.