Issue 3, 1988

Observation of excimer formation in the covalent adducts of 9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene-7,8-diol with poly(dG-dC)

Abstract

The covalent binding of 9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene-7,8-diol to alternating poly(dG–dC) results in extensive occurrence of excimers as shown by fluorescence spectroscopy; the origin is inferred to be close-lying pyrene chromophores bound to guanines in the minor groove of DNA.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1988, 211-212

Observation of excimer formation in the covalent adducts of 9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene-7,8-diol with poly(dG-dC)

M. Eriksson, B. Nordén, B. Jernström, A. Gräslund and P. Lycksell, J. Chem. Soc., Chem. Commun., 1988, 211 DOI: 10.1039/C39880000211

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