Synthesis of antifungal antibiotic A25822 factor A
Abstract
An intramolecular aza-Witting cyclization reaction has been employed as a key step in the preparation of the antifungal antibiotic A25822 factor a from ergosterol.
An intramolecular aza-Witting cyclization reaction has been employed as a key step in the preparation of the antifungal antibiotic A25822 factor a from ergosterol.
R. E. Dolle and L. I. Kruse, J. Chem. Soc., Chem. Commun., 1988, 133 DOI: 10.1039/C39880000133
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