Issue 12, 1987

Electrophilic substitution of heteroaromatic compounds. Part 54. Intramolecular base-catalysed hydrogen exchange at the 3-position in substituted pyridines

Abstract

Various O-linked substituents at the 4-position of a pyridine ring enhance the rate of base-catalysed hydrogen exchange at the 3,5-ring positions. An intramolecular proton-abstraction mechanism is proposed.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 2, 1987, 1867-1869

Electrophilic substitution of heteroaromatic compounds. Part 54. Intramolecular base-catalysed hydrogen exchange at the 3-position in substituted pyridines

A. R. Katritzky and R. Murugan, J. Chem. Soc., Perkin Trans. 2, 1987, 1867 DOI: 10.1039/P29870001867

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