Issue 0, 1987

A new flexible synthesis of (R,S)-mevalonolactone

Abstract

By selective ozonolysis of the diene (5), a new synthesis of (R,S)-mevalonolactone (1a) has been developed, which can be adapted to other compounds related to (1a). This has been exemplified by the synthesis of the monodeuteriated triol (4d) and dideuteriated mevalonolactone (1d).

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1987, 2301-2303

A new flexible synthesis of (R,S)-mevalonolactone

P. Ferraboschi, R. Canevotti, P. Grisenti and E. Santaniello, J. Chem. Soc., Perkin Trans. 1, 1987, 2301 DOI: 10.1039/P19870002301

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