Issue 0, 1987

New approaches to the synthesis of β-lactam antibiotics

Abstract

The selective syntheses of carbapenams and carbacephams are described from the same intermediate by application of appropriate experimental conditions using radical cyclisation techniques. The carbapenams were synthesised diastereoselectively by a 5-exo trig cyclisation.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1987, 1237-1242

New approaches to the synthesis of β-lactam antibiotics

J. Knight and P. J. Parsons, J. Chem. Soc., Perkin Trans. 1, 1987, 1237 DOI: 10.1039/P19870001237

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