Issue 23, 1987

Novel non-basic bioisostere of histidine synthesized from L-aspartic acid

Abstract

The incorporation of the novel bioisostere (1c) of histidine into a tripeptide led to a very potent and specific renin inhibitor.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1987, 1792-1793

Novel non-basic bioisostere of histidine synthesized from L-aspartic acid

H. L. Sham, H. Stein and J. Cohen, J. Chem. Soc., Chem. Commun., 1987, 1792 DOI: 10.1039/C39870001792

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