Issue 21, 1987

The isolation and characterisation of (3R,5R)- and (3S,5R)-carbapenam-3-carboxylic acid from Serratia and Erwinia species and their putative biosynthetic role

Abstract

Two new β-lactams (4b) and (5b), and (3S,5R)-carbapenam-3-carboxylic acid, have been isolated from strains of Serratia and Erwinia spp.; their possible role, and that of (5R)-carbapen-2-em-3-carboxylic acid as intermediates in the biosynthesis of the more complex members of the carbapenem family of β-lactam antibiotics is discussed.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1987, 1623-1625

The isolation and characterisation of (3R,5R)- and (3S,5R)-carbapenam-3-carboxylic acid from Serratia and Erwinia species and their putative biosynthetic role

B. W. Bycroft, C. Maslen, S. J. Box, A. G. Brown and J. W. Tyler, J. Chem. Soc., Chem. Commun., 1987, 1623 DOI: 10.1039/C39870001623

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